CH414-15 Advanced Molecular Pharmacology
Introductory description
N/A
Module aims
The aim of the module is to describe current developments, methods and techniques in drug design and drug discovery in the pharmaceutical industry. The module is given by representatives of major pharmaceutical companies, who present case studies and techniques in modern drug discovery and drug development.
The module also aims to develop transferable skills. This module is assessed by 100% assessed work via team presentation of an assigned topic in medicinal chemistry, an oral presentation, and an individual written assignment on current medicinal chemistry.
Outline syllabus
This is an indicative module outline only to give an indication of the sort of topics that may be covered. Actual sessions held may differ.
Lectures will be presented by senior scientists from the pharmaceutical industry. Each visiting lecturer will present 1-2 lectures describing case studies in modern drug design and drug discovery. The precise content lectures will vary according to the areas of research & development of the visiting lecturers. Current lecturers and syllabus as follows:
Dr. Peter North (GSK) Discovery of sumitriptan for treatment of migraine.
Dr. David Fox (Funxional Therapeutics). Discovery of chemokine receptor antagonists
Dr. Paul Davis (Mologic). The human immune system, therapeutic & technological applications of antibodies
Dr. Magnus Walter (Lilly Research). Discovery of monoamine re-uptake inhibitors as anti-depressants
Dr. Prem Meghani (Sygnature). G-protein-coupled receptors as chemotherapeutic targets
Dr. John Pollard (Vertex) Enzyme inhibition, inhibitors of protein kinases
Dr. Andrew Merritt (MRC Tech) Combinatorial chemistry & high-throughput screening
Learning outcomes
By the end of the module, students should be able to:
- Describe and present current advances in drug design, drug discovery and drug development.
- Make an effective written presentation of current medicinal chemistry literature work.
- Work effectively in a team in order to research and present a report and oral presentation in the area of current drug discovery.
Indicative reading list
Medicinal Chemistry, G.L. Patrick, OUP, Oxford, 2013
The Organic Chemistry of Drug Design and Drug Action, R.B. Silverman, Aacdemic Press, 1992.
Research element
e.g. essay, dissertation, individual or group research, research skills activity, etc.
Interdisciplinary
e.g. co-taught with another department or with an industry perspective, bridges two or more disciplinary concepts, ideas, etc.
Subject specific skills
Written communication
Teamwork
Information literacy and research skills
Transferable skills
Written communication
Teamwork
Information literacy and research skills
Study time
| Type | Required |
|---|---|
| Lectures | 12 sessions of 1 hour (8%) |
| Other activity | 3 hours (2%) |
| Private study | 135 hours (90%) |
| Total | 150 hours |
Private study description
60 hr student self-study for individual assignment
15 hr student group meetings for group project
60 hr student self-study for group project
Other activity description
3 hr oral presentation session
Costs
No further costs have been identified for this module.
You do not need to pass all assessment components to pass the module.
Students can register for this module without taking any assessment.
Assessment group A1
| Weighting | Study time | Eligible for self-certification | |
|---|---|---|---|
Assessment component |
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| Assignment (3000 words) | 40% | Yes (extension) | |
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Individual assignment (3000 Words) |
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Reassessment component is the same |
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Assessment component |
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| Team-based assignment (12,500 words) | 40% | No | |
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Team-based assignment (12500 Words) 5 or 6 students |
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Reassessment component is the same |
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Assessment component |
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| Management report of team-based assignment | 4% | No | |
Reassessment component is the same |
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Assessment component |
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| Oral presentation | 16% | No | |
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Presentations should last for 20 minutes (plus 5 minutes for questions). |
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Reassessment component is the same |
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Feedback on assessment
Individual assignment, group project written report and oral presentation are double-marked by two members of academic staff, written feedback within 20 days. Cohort level examination feedback provided via Moodle.
Courses
This module is Core for:
- Year 4 of UCHA-F110 Undergraduate Master of Chemistry (with Industrial Placement)