The aim of this module is to achieve an overview of the immune system with a focus on adaptive immunity.
By the end of the course you will have a good understanding of the main molecular and cellular players in the immune system and how they interact.
You should have a good conceptual grasp of the role of the immune system in defining self from non-self and how T cells and B cells acquire this discrimination.
You should also be able to understand how important the balance of the immune system is and what happens when the normal status quo is disrupted.
The aim of this module is to introduce students to one of the fundamental processes that underpin modern biomedical science: immunology. It builds on the materila delivered in BS127 Agents of infectious disease and provides the preliminary understadning for the finaly year module BS317 Advanced Immunlogy. Together with companion modules dealing with specific pathogens, the module considers many disease processes and their mitigation. Immunology deals with the basic processes of immunity to infection, but also covers aspect of hypersentitivity and auto-immune disease.
This is an indicative module outline only to give an indication of the sort of topics that may be covered. Actual sessions held may differ.
Immunology is presented as an overview of the immune system with a focus on T cell immunity, including:
- Recognition of antigen by the adaptive immune system.
- The TCR and MHC
- T-cell mediated immunity
- The humoral immune response
- Failure of immunity: evasion and subversion and immunodeficiency disease.
- Mucosal immunity
- Inappropriate activation: allergy and autoimmune disease
- Case studies of immune system disregulation and disease, including rheumatoid arthritis,
multiple sclerosis, and Crohn’s disease
By the end of the module, students should be able to:
- By the end of the module the students should have a good understanding of the basics of the innate and adaptive immune response with a focus on the adaptive immune response and the generation of diversity. Student will be able to apply these fundamentals to the progression and mitigation of infectious disease.
Indicative reading list
There are many good Immunology books for this level the rcourse recommended is Murphy, K. M., Travers, P. and Walport, M. Janeway’s Immunobiology, latest edn. (Garland Science).
Subject specific skills
Explain the main molecular and cellular players in the innate and adaptive immune system and their interaction.
Explain the role of the immune system in defining self from non-self and how T cells and B cells acquire this discrimination.
Understand how important the balance of the immune system is what happens when the normal status quo is disrupted in disease examples
Self directed learning
|Lectures||15 sessions of 1 hour (12%)|
|Supervised practical classes||1 session of 1 hour (1%)|
|Private study||104 hours (87%)|
Private study description
Self directed learning and revision for the final exam
No further costs have been identified for this module.
You do not need to pass all assessment components to pass the module.
Students can register for this module without taking any assessment.
Assessment group B1
|1.5 hour online examination (Summer)||100%|
Option examination is essay examination. You will have 1 hour to write 2 essays out of a choice of 3 titles.
Feedback on assessment
Final examination feedback is given to returning students as generalised feedback on what constituted a good essay; common mistakes/misconceptions and good practise are identified and shared.\r\n\r\n
This module is Optional for:
- Year 2 of UBSA-4 Undergraduate Biological Sciences (with Intercalated Year)